Basophil Activation Test for the In Vitro Diagnosis of Tocilizumab Hypersensitivity

Key Points

• This study aims to evaluate the effectiveness of the basophil activation test (BAT) in diagnosing tocilizumab hypersensitivity.
• Performed a basophil activation test to assess allergic reactions to tocilizumab.
• Compared BAT results with skin tests and IgE measurements.
• Analyzed the correlation between IgE-allergenic activity and hypersensitivity symptoms.
• BAT successfully detected hypersensitivity reactions not identified by traditional methods.
• Findings indicate BAT's superior sensitivity for diagnosing tocilizumab allergies.
• Correlation found between BAT results and observed allergic symptoms.