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Investigation reveals thrombophilia significantly contributes to retinal vein occlusion, suggesting important implications for treatment.
Multifactorial hereditary thrombophilia was found in patients with retinal vein occlusion in 78.7% of cases, and in 21.3% of cases in combination with lupus anticoagulant (LA). The combination of mutations and polymorphisms in hemostasis genes in patients with retinal vein occlusion (RVO) affects markers of endothelial damage, activating components of the hemostatic system, which clinically manifests as a local thrombohemorrhagic syndrome in the retinal microcirculatory bed.
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Шелковникова et al. (2025) studied this question.
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