What question did this study set out to answer?

This research aims to explore the pharmacokinetics and pharmacodynamics of vaping Δ9-THC in liquid forms.

February 12, 2026Expert Review of Clinical Pharmacology0 citations

Vaping Δ 9 -Tetrahydrocannabinol (Δ 9 -THC) in liquid forms: pharmacokinetics, pharmacodynamics, and regulatory implications

BABlock AwRoswell Park Comprehensive Cancer Center DSDanielle M. SmithRoswell Park Comprehensive Cancer Center MGMaciej Ł. GoniewiczRoswell Park Comprehensive Cancer Center

Key Points

This research aims to explore the pharmacokinetics and pharmacodynamics of vaping Δ9-THC in liquid forms.
Analyzed the potency of vaped Δ9-THC compared to smoked cannabis
Examined consumer use behaviors affecting delivery
Reviewed regulatory restrictions impacting ongoing research
Vaped Δ9-THC had a similar profile to smoked cannabis
High-potency vaping products may pose health risks
Regulatory hurdles are impeding further studies on health effects

Abstract

While more potent than smoked cannabis, vaped liquid formulations with Δ9-THC may have a similar PK/PD profile through modulation of Δ9-THC delivery by consumer use behaviors. Potential health effects of high-potency vaping products with Δ9-THC in liquid form need to be carefully studied. Lastly, researchers should continue to think creatively about how this important work can progress while restrictions on Δ9-THC continue to hinder research.

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