A novel ratiometric electrochemical aptasensor based on βcyclodextrinylated graphene and Fc/β-CD host-guest recognition for ultrasensitive detection of Zearalenone

Key Points

• The aim is to develop a highly sensitive aptasensor for detecting zearalenone, a harmful mycotoxin.
• Designed a ratiometric electrochemical aptasensor utilizing β-cyclodextrinylated graphene.
• Implemented host-guest recognition between Fc and β-CD for improved sensing.
• Conducted tests to evaluate the sensitivity of the sensor to zearalenone.
• Achieved ultrasensitive detection of zearalenone in various samples.
• Demonstrated a significant reduction in detection limits compared to conventional methods.
• Highlighted the effectiveness of the aptasensor in real-world grain samples.