What question did this study set out to answer?

To evaluate the efficacy and safety of poly-L-lactic acid for midface rejuvenation.

February 12, 20264 citations

Efficacy and Safety of Poly-L-lactic Acid (PLLA) for Midface Rejuvenation: A 12-month Split-face Controlled Evaluation With 3D Imaging and Patient-reported Outcomes.

MPMartina Ponzo MLMariagiovanna LombardiFederico II University Hospital SAStefano AvvedimentoAmerican Society of Plastic Surgeons

Key Points

To evaluate the efficacy and safety of poly-L-lactic acid for midface rejuvenation.
Controlled split-face evaluation
Standardized PLLA treatment
12-month duration
95-patient cohort
Assessment of patient-reported outcomes
Measurable, long-lasting midfacial volume restoration
No granulomas or delayed-onset nodules observed
High levels of patient satisfaction
Favorable safety profile for the PLLA formulation

Abstract

Controlled split-face evaluation demonstrated that standardized PLLA treatment yields measurable, long-lasting midfacial volume restoration with excellent safety and high patient satisfaction. No granulomas or delayed-onset nodules were observed in this 12-month, 95-patient cohort, supporting a favorable safety profile for this PLLA formulation under these study conditions.

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Cite This Study

Ponzo et al. (Mon,) studied this question.

synapsesocial.com/papers/698d6ebb5be6419ac0d547ab https://doi.org/https://doi.org/10.1093/asj/sjag039

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