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February 12, 2026International Journal of BiomaterialsOpen Access

Effect of Moringa oleifera Protein‐Coated Gold Nanoparticles as Naturally Derived Disruptors of Biofilms

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LMLakshmi Sudhir MenonBirla Institute of Technology and Science, Pilani - Goa Campus NGNarendranath GhoshBirla Institute of Technology and Science, Pilani SBSumit BiswasPhilipps University of Marburg

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Implication

Demonstrates the ability of Moringa oleifera protein-coated gold nanoparticles to effectively disrupt biofilms in Staphylococcus aureus infections, suggesting a novel treatment approach.

Key Points

This research aims to explore the effectiveness of Moringa oleifera protein-coated gold nanoparticles against biofilm formation by Staphylococcus aureus.
Conjugated Moringa oleifera protein p62 with gold nanoparticles (AuNPs).
Evaluated the adsorption and stability of p62-AuNPs using microscopy.
Measured binding kinetics via plasmon resonance.
Assessed biofilm disruption and cell viability through confocal imaging.
P62-coated AuNPs effectively disintegrated mature Staphylococcus aureus biofilms.
Demonstrated a more efficient disruption than p62 alone.
Induced cell death and altered coccal morphology.
Showed non-cytotoxic effects on human myoblast C2C12 cell lines.

Cite This Study

Menon et al. (2026) studied this question.

synapsesocial.com/papers/698d6ebb5be6419ac0d54890 https://doi.org/10.1155/ijbm/1381604

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Implication

Demonstrates the ability of Moringa oleifera protein-coated gold nanoparticles to effectively disrupt biofilms in Staphylococcus aureus infections, suggesting a novel treatment approach.

Effect of Moringa oleifera Protein‐Coated Gold Nanoparticles as Naturally Derived Disruptors of Biofilms

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Cite This Study

Effect of Moringa oleifera Protein‐Coated Gold Nanoparticles as Naturally Derived Disruptors of Biofilms

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Implication

Key Points

Cite This Study

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