Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 12, 2026European Journal of NeurologyOpen Access

Associated Autoimmunity in Myasthenia Gravis in Denmark: A Nationwide Case–Control Study

View Full Paper
Ask AI
Bookmark
Share

Authors

JNJosefine Jul Jarbæk NielsenLLLotte LevisonHAHenning Andersen

Discussion

Loading...

Member takes

Overview

A case–control study observes autoimmunity associations in myasthenia gravis patients, implying shared risks.

Key Points

  • This study investigates the relationship between myasthenia gravis (MG) and other autoimmune diseases (ADs).
  • Nationwide, population-based case–control study conducted from 1985 to 2020.
  • Matched 2110 MG patients with 21,100 controls by age, sex, and index date.
  • Used conditional logistic regression for estimating odds ratios for AD diagnoses prior to MG.
  • Applied Cox regression to assess hazard ratios for AD diagnoses after MG.
  • 5.2% of MG patients had an AD diagnosis before onset, compared to 2.7% of controls (OR 1.9).
  • 5.0% of MG patients received an AD diagnosis after MG, compared to 2.7% of controls (HR 2.1).
  • Stronger associations were noted particularly in females and those ≤ 50 years.
  • Autoimmune thyroiditis, systemic lupus erythematosus, and pernicious anemia showed the strongest links.

Cite This Study

Nielsen et al. (2026) studied this question.

synapsesocial.com/papers/698d6eca5be6419ac0d54908https://doi.org/10.1111/ene.70498
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rate of Autoimmune Diseases in the 10 Years Preceding Myasthenia Gravis Diagnosis2026
  2. 2Autoimmune and Non-Autoimmune Comorbidities in Myasthenic Patients of East-European Descent: A Case–Control Study2024 · 7 citations
  3. 3Autoimmune thyroid disease and myasthenia gravis: a study bidirectional Mendelian randomization2024 · 10 citations
  4. 4Comorbidity in myasthenia gravis: multicentric, hospital-based, and controlled study of 178 Italian patients2024 · 51 citations
  5. 5Clinical and epidemiological aspects of patients with myasthenia gravis in a tertiary center2024