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To investigate how gestational age affects clinical and MRI characteristics in infants with unilateral cerebral palsy.

Characteristics of unilateral cerebral palsy according to gestational age at birth: A retrospective study

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To investigate how gestational age affects clinical and MRI characteristics in infants with unilateral cerebral palsy.
Retrospective study of infants with unilateral cerebral palsy from the Canadian CP Registry.
Consideration of gestational age as continuous and categorical variables.
Evaluation of neonatal signs such as encephalopathy and seizures.
Use of multivariable and multinomial regression to analyze relationships.
Out of 826 participants, 69.3% were born at term, while 14.6% and 16.1% were born moderate-to-late preterm and very-to-extremely preterm, respectively.
Neonatal signs like encephalopathy and seizures were less common in infants born at moderate-to-late preterm gestational age (OR = 0.24).
Focal injury was the most common MRI pattern (68.2%), and it increased with gestational age (OR = 1.06).
White matter injury decreased with gestational age (OR = 0.88).
Impairments were independent of gestational age but related to specific MRI patterns.

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A retrospective analysis investigates MRI and clinical features of unilateral cerebral palsy related to gestational age.

Piché et al. (2026) studied this question.

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