Bioaccessible sulforaphane attenuates oxidative stress-driven parainflammation in intestinal epithelial cells

Concepción Medrano-Padial; Sonia Medina; C. Garcia-Viguera; Raúl Domínguez‐Perles

doi:10.1039/d5fo03038b

January 1, 2026Food & FunctionOpen Access

Bioaccessible sulforaphane attenuates oxidative stress-driven parainflammation in intestinal epithelial cells

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Key Points

The aim is to investigate how sulforaphane affects oxidative stress and inflammation in intestinal epithelial cells.
Utilized plant-based dietary sources of sulforaphane and glucoraphanin.
Examined effects on oxidative stress levels in intestinal epithelial cells.
Assessed inflammation markers pre- and post-intervention.
Sulforaphane significantly reduced levels of oxidative stress in cells.
Marked improvements in inflammation markers were observed after treatment with sulforaphane.

Implication

This research demonstrates that sulforaphane reduces inflammation in intestinal epithelial cells, suggesting potential health benefits.

Abstract

The dietary consumption of plant-based foods rich in sulforaphane (SFN) and its precursor, glucoraphanin, contributes to health due to SFN's ability to mitigate inflammation. Based on this premise, the present...

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Cite This Study

Medrano-Padial et al. (2026) studied this question.

synapsesocial.com/papers/698d6f0d5be6419ac0d5515c https://doi.org/10.1039/d5fo03038b

View Full Paper

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Bioaccessible sulforaphane attenuates oxidative stress-driven parainflammation in intestinal epithelial cells

Key Points

Implication

Abstract

Discussion

Cite This Study

Bioaccessible sulforaphane attenuates oxidative stress-driven parainflammation in intestinal epithelial cells

Key Points

Implication

Abstract

Discussion

Cite This Study

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