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August 22, 2012JAMA1,131 citationsOpen Access

Comparison of Novel Risk Markers for Improvement in Cardiovascular Risk Assessment in Intermediate-Risk Individuals

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JYJoseph YeboahRMRobyn L. McClellandTPTamar S. Polonsky

Key Result

Coronary artery calcium was the superior predictor for incident CHD/CVD compared to ankle-brachial index, high-sensitivity CRP, and family history in intermediate-risk individuals.

Structured PICO

Does coronary artery calcium provide superior risk discrimination for incident CHD/CVD compared to other novel risk markers in intermediate-risk individuals?

P
Population
Intermediate-risk individuals
I
Intervention
Assessment of coronary artery calcium
C
Comparator
Assessment of ankle-brachial index, high-sensitivity CRP, and family history
O
Outcome
Incident CHD/CVD (discrimination and risk reclassification)hard clinical

Coronary artery calcium is superior to ankle-brachial index, high-sensitivity CRP, and family history for predicting incident cardiovascular events and reclassifying risk in intermediate-risk individuals.

Abstract

Coronary artery calcium, ankle-brachial index, high-sensitivity CRP, and family history were independent predictors of incident CHD/CVD in intermediate-risk individuals. Coronary artery calcium provided superior discrimination and risk reclassification compared with other risk markers.

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Cite This Study

Yeboah et al. (2012) studied this question. Coronary artery calcium was the superior predictor for incident CHD/CVD compared to ankle-brachial index, high-sensitivity CRP, and family history in intermediate-risk individuals.

synapsesocial.com/papers/698e30bae3d33b50e18365cfhttps://doi.org/10.1001/jama.2012.9624
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