Dual-chamber leadless pacemaker implantation in an 84-year-old woman with ATTR amyloidosis initially failed atrial capture but showed atrial capture at Day 3 and improved pacing thresholds from 3.0 V to 0.5 V over 2 months.
Case Report (n=1)
No
In patients with ATTR amyloidosis undergoing atrial leadless pacemaker implantation, stable current of injury and impedance may predict delayed threshold improvement despite initial capture failure, potentially avoiding risky and unnecessary device repositioning.
Effect estimate: Improvement in pacing threshold from no capture at implantation to 0.5 V at 1.5 ms pulse width at 2 months
ATTR amyloidosis patient with initial atrial capture failure showed delayed threshold improvement over time. Stable current of injury and impedance guided expectant management, avoiding unnecessary device repositioning while achieving successful outcomes.
Takada et al. (Sun,) conducted a case report in Elderly patient (84-year-old woman) with ATTR cardiac amyloidosis and sinus node dysfunction with recurrent syncope and bradycardia (n=1). Dual-chamber leadless pacemaker (Aveir DR, Abbott) implantation was evaluated on Atrial pacing capture and threshold improvement over time post atrial leadless pacemaker implantation (Improvement in pacing threshold from no capture at implantation to 0.5 V at 1.5 ms pulse width at 2 months). Dual-chamber leadless pacemaker implantation in an 84-year-old woman with ATTR amyloidosis initially failed atrial capture but showed atrial capture at Day 3 and improved pacing thresholds from 3.0 V to 0.5 V over 2 months.