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January 1, 2026Acta Cirúrgica BrasileiraOpen Access

RETRACTION: Atractylenolide III alleviates sepsis-mediated lung injury via inhibition of FoxO1 and VNN1 protein

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Key Points

This work aimed to explore how Atractylenolide III affects lung injury caused by sepsis.
Analyzed the efficacy of Atractylenolide III in a sepsis model
Examined interactions with FoxO1 and VNN1 proteins
Atractylenolide III improved lung injury outcomes
Decreased activity of FoxO1 and VNN1 proteins

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Implication

Retraction of findings revealing how Atractylenolide III reduces lung damage from sepsis, suggesting new treatment options.

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Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/698ebeb185a1ff6a93016015 https://doi.org/10.1590/acb360802.retraction

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1D101-11 The Ptp4a3 Inhibitor, Kvx-053, Protects Against the Development of Sepsis-induced AliOriginal Research · 2026
2Drug Repurposing Screen Identifies Foxo1-Dependent Angiopoietin-2 Regulation in Sepsis*preclinical · 2015 · 46 citations
3Senegenin Alleviates Acute Lung Injury Induced by Sepsis via Promoting the Expression of Clara Cell Protein 162025
4Wogonin alleviates sepsis-induced acute lung injury by modulating macrophage polarization through the SIRT1-FOXO1 pathways2024 · 7 citations
5Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX32025 · 1 citations

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