Classifying Parkinson’s Disease Progression via Latent Trajectories of Striatal Specific Binding Ratios from I-123 FP-CIT SPECT in Association with Levodopa-Induced Dyskinesia | Synapse
Classifying Parkinson’s Disease Progression via Latent Trajectories of Striatal Specific Binding Ratios from I-123 FP-CIT SPECT in Association with Levodopa-Induced Dyskinesia
The aim is to classify the progression of Parkinson’s disease by analyzing imaging trajectories and their relationship with levodopa-induced dyskinesia.
Conducted longitudinal imaging using I-123 FP-CIT SPECT.
Analyzed striatal specific binding ratios over time.
Integrated clinical characteristics with imaging data.
Found contemporaneous associations between imaging data and LID occurrence.
Identified potential clinically relevant insights for disease progression classification.
Abstract
Longitudinal imaging trajectories demonstrate contemporaneous associations with LID occurrence in PD and may provide clinically relevant insights when combined with clinical characteristics.