A meta-analysis identifies glymphatic impairment as a potential biomarker in traumatic brain injury, suggesting need for standard protocols.
TBI is associated with significantly reduced DTI-ALPS values, with more prominent deteriorations over the long term, supporting its potential as a biomarker of glymphatic impairment. However, methodological heterogeneity emphasizes the need for standardized protocols and longitudinal studies to establish clinical utility.
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Lomer et al. (2026) studied this question.
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