Tumor control probability analysis in carbon-ion radiotherapy for prostate cancer considering the oxygen effect

February 10, 2026Physica MedicaOpen Access

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Key Points

This research aims to analyze the tumor control probability in prostate cancer treatments using carbon-ion radiotherapy while considering the oxygen effect.
Analyzed the tumor control probability (TCP) in prostate cancer using carbon-ion radiotherapy.
Considered the oxygen enhancement ratio (OER) compared to photon therapies.
Evaluated the effectiveness against hypoxic tumors.
Carbon-ion therapy showed a lower oxygen enhancement ratio than photon therapy.
Indicated potential for improved control of hypoxic tumors in prostate cancer.

Analysis highlights improved tumor control in prostate cancer using carbon-ion therapy, implying effective treatment for challenging tumors.

The carbon-ion SOBP used in prostate cancer treatment has a lower OER than photons, suggesting its potential effectiveness against hypoxic tumors.

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Wakisaka et al. (2026) studied this question.

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