The expression pattern and clinical implications of TBC1D16 in hepatocellular carcinoma | Synapse
February 14, 2026
The expression pattern and clinical implications of TBC1D16 in hepatocellular carcinoma
Key Points
This research examines the expression of TBC1D16 in hepatocellular carcinoma and its implications for prognosis and diagnosis.
Analyzed TBC1D16 expression levels in hepatocellular carcinoma samples
Investigated the impact of TBC1D16 silencing on NF-κB signaling
Evaluated correlations between TBC1D16 levels and clinical outcomes
Upregulation of TBC1D16 is associated with poor prognosis in HCC patients
Silencing TBC1D16 results in the activation of NF-κB signaling
Higher TBC1D16 expression correlates with increased tumor invasiveness
Abstract
TBC1D16 upregulation in HCC is linked to poor prognosis and enhances tumor invasiveness, silencing TBC1D16 activates NF-κB signaling, indicating its potential role in HCC diagnosis.