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Demonstrates enhanced plant resistance through E3 ligase and effector interaction in rice, suggesting a novel control strategy.
The rice blast fungal effector AVR-PikC binds to the rice protein HIPP19, which may contribute to plant susceptibility. The compound B93 induces the interaction between the rice E3 ligase APIP6 and AVR-PikC, which results in the ubiquitination and degradation of AVR-PikC, thereby facilitating plant resistance.
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Chang et al. (2026) studied this question.
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