This review demonstrates diverse heat hormesis regimens improve stress resilience in Caenorhabditis elegans, suggesting therapeutic potential for health applications.
Key Points
This review aims to synthesize molecular and phenotypic findings related to heat hormesis in C. elegans.
Review of heat hormesis studies in C. elegans
Organization of findings by regimen type
Comparison of temperature, duration, and developmental stages of priming
Discussion of knowledge gaps and future experimental design considerations
Low heat stress enhances lifespan and stress resilience in C. elegans
Different regimens show both shared and unique physiological outcomes
Conserved mechanisms identified across species highlight potential therapeutic applications