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February 14, 2026Journal of Animal Breeding and GeneticsOpen Access

Unravelling the Genetic Mechanisms of Litter Traits in a Maternal Line of Pigs

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Authors

GOGuilherme OselameUniversidade do Estado de Santa CatarinaSPSuelen Fernandes PadilhaUniversidade Federal do ParanáMCMaurício Egídio CantãoConcordia University Wisconsin

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Implication

This research identifies genomic regions associated with litter traits in pigs, suggesting new breeding strategies for efficiency.

Key Points

  • The study aims to estimate genetic parameters and identify genomic regions linked to litter traits in pigs.
  • Used 17,011 phenotypic records and 190,000 pedigree records from a Large White female line.
  • Genotyped 4,366 animals using Illumina 50 K and 80 K panels.
  • Estimated heritability, genetic and phenotypic correlations, and performed genome-wide association studies (GWAS).
  • Investigated candidate genes using the Ensembl database and additional bioinformatics tools.
  • Identified 14 significant genomic windows for total number born (TNB), 10 for number born alive (NBA), and 15 for viable piglets at Day 5 (PV5).
  • Mapped 157 genes for TNB, 101 for NBA, and 140 for PV5 across 10 chromosomes.
  • Common genes across traits include ESR1, THRB, SLIT2, and ZBTB2, linked to hormonal regulation, embryogenesis, and immunity.

Cite This Study

Oselame et al. (2026) studied this question.

synapsesocial.com/papers/699011812ccff479cfe584a7https://doi.org/10.1111/jbg.70042
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