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November 24, 2004JAMA

Obesity and the Risk of New-Onset Atrial Fibrillation

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Why the study?

Does obesity increase the risk of new-onset atrial fibrillation?

Design

Cohort

Authors

Thomas J. Wang
Thomas J. WangHeart Failure / Cardiomyopathy

Discussion

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Overview

LA dilatation may mediate obesity-AF risk; extends observational mediation data but leaves causal targets open.

Structured PICO

Does obesity increase the risk of new-onset atrial fibrillation?

I
Intervention
Obesity (exposure)
O
Outcome
New-onset atrial fibrillationhard clinical

Obesity is a potentially modifiable risk factor for new-onset atrial fibrillation, with the risk appearing to be mediated by left atrial dilatation.

Cite This Study

Thomas J. Wang (2004) studied this question.

synapsesocial.com/papers/6991ff751c7ab1ded6fb2f80https://doi.org/10.1001/jama.292.20.2471

Topics

Atrial fibrillationPersistent AF management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study.1994 · 1,077 citations
  2. 2Electrical, contractile and structural remodeling during atrial fibrillation2002 · 1,462 citations
  3. 3Obstructive Sleep Apnea and the Recurrence of Atrial Fibrillation2003 · 985 citations
  4. 4Body Size and Fat Distribution as Predictors of Coronary Heart Disease among Middle-aged and Older US Men1995 · 844 citations
  5. 5Impaired Atrial M2-Cholinoceptor Function in Obesity-Related Hypertension1999 · 53 citations