Novel acetohydroxamic acid strategy improves chemical protein synthesis using peptide ligation.
We here report a novel acetohydroxamic acid-assisted peptide hydrazide ligation (APHL) strategy for chemical protein synthesis. With acetohydroxamic acid serving as a non-thiol additive, sodium nitrite-activated peptide hydrazides are in...
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Zhao et al. (2025) studied this question.
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