What question did this study set out to answer?

To evaluate and compare the incidence of central line-associated bloodstream infections at different catheter insertion sites in critically ill patients.

February 16, 2026BMC Infectious DiseasesOpen Access

The risk of central line-associated bloodstream infection between internal jugular and subclavian sites in critically ill patients: a multicenter cohort study

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To evaluate and compare the incidence of central line-associated bloodstream infections at different catheter insertion sites in critically ill patients.
Multicenter cohort study involving critically ill patients
Comparison of CVCs placed in internal jugular and subclavian sites
Incidence calculated using Poisson regression
Risk assessed via univariable and multivariable Cox proportional hazards regression models
Internal jugular site used in 68.3% of cases (1,626 out of 2,379 patients)
Overall CLABSI incidence was low, with 19 documented over 18,359 CVC days
Incidence rate was 1.22 per 1000 CVC days for internal jugular and 0.66 for subclavian site
No significant association found between insertion site and CLABSI risk in adjusted analyses

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Implication

Cohort study shows similar CLABSI risk in critically ill patients with central venous catheters, highlighting the need for larger trials.

Cite This Study

He et al. (2026) studied this question.

synapsesocial.com/papers/69926a620d0ce0adc9976a5d https://doi.org/10.1186/s12879-026-12837-2

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The risk of central line-associated bloodstream infection between internal jugular and subclavian sites in critically ill patients: a multicenter cohort study

Key Points

Discussion

Implication

Cite This Study

The risk of central line-associated bloodstream infection between internal jugular and subclavian sites in critically ill patients: a multicenter cohort study

Key Points

Discussion

Implication

Cite This Study

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