The genomic diversity of SARS-CoV-2 Omicron lineages collected during routine sentinel surveillance in Tanzania between November 2022 and July 2023

Lawrence Amon Mapunda; Maria Ezekiely Kelly; Shimba Henerico; Monica Francis; Azizi H. Ituka; Omega Machange; Adela Kisanga; Jackson Peter Mushumbusi; Ferdinand Ndunguru; Ibrahim Ireneus Mauki; Olympia Godbless Machange; Robert Baluhya; Japhet Msuya; Ramdhani Libenanga; Ambele Mwafulango; Peter Van Heusden; Seth Inzaule; Gerald Misinzo; Nyambura Moremi

doi:10.1186/s12864-026-12656-4

Key Points

The aim is to investigate the genetic diversity and transmission patterns of SARS-CoV-2 Omicron lineages in Tanzania.
Conducted genomic analysis on SARS-CoV-2 samples collected from sentinel surveillance sites.
Identified and categorized sixteen Omicron lineages through sequencing.
Examined regional lineage distribution to detect specific clades.
Identified dominance of clades 22 F (XBB) and 22E (BQ.1) in Tanzania.
Detected regional variations in the distribution of different Omicron lineages.
Found evidence suggesting sustained local transmission of specific lineages.

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Implication

Genomic analysis examines transmission dynamics and lineage distribution of SARS-CoV-2 in Tanzania, indicating sustained local spread.

Abstract

This study provides key insights into the genetic diversity and transmission dynamics of SARS-CoV-2 in Tanzania. It highlights regional discrepancies in lineage distribution, identifying sixteen Omicron lineages and the dominance of clades 22 F (XBB*) and 22E (BQ.1) in the country. The presence of Tanzania-specific clades suggests sustained local transmission of the virus. These findings underscore the importance of enhanced integrated genomic surveillance systems and ongoing monitoring of SARS-CoV-2 evolution.

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Cite This Study

Mapunda et al. (2026) studied this question.

synapsesocial.com/papers/6992b4919b75e639e9b098f3 https://doi.org/10.1186/s12864-026-12656-4

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The genomic diversity of SARS-CoV-2 Omicron lineages collected during routine sentinel surveillance in Tanzania between November 2022 and July 2023

Key Points

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Implication

Abstract

Discussion

Cite This Study

The genomic diversity of SARS-CoV-2 Omicron lineages collected during routine sentinel surveillance in Tanzania between November 2022 and July 2023

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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