A Case of Refractory Adult-Onset Still Disease With Macrophage Activation Syndrome and Pulmonary Alveolar Proteinosis

Key Points

• This case report aims to describe a patient with refractory adult-onset still disease and its complications.
• Detailed case analysis of an adult patient with refractory AOSD.
• Assessment of treatment response to glucocorticoids and biologic agents.
• Evaluation of associated pulmonary alveolar proteinosis.
• Patient presented with refractory symptoms despite standard glucocorticoids and biologic treatment.
• Developed macrophage activation syndrome and pulmonary alveolar proteinosis as complications.