What question did this study set out to answer?

This research aims to compare the effectiveness of unilateral versus bilateral ultrasound in detecting joint inflammation in clinically suspect arthralgia patients.

February 17, 2026The Journal of Rheumatology

Unilateral versus bilateral ultrasound of the hands in patients with clinically suspect arthralgia: what is the difference? A longitudinal study

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Authors

ABAnna M.P. BoerenErasmus University Rotterdam EOE.H. OeiErasmus MC AWAnnemiek WillemzeMaasstad Ziekenhuis

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Implication

Longitudinal study reveals that unilateral ultrasound predicts inflammatory arthritis similarly to bilateral scan.

Key Points

This research aims to compare the effectiveness of unilateral versus bilateral ultrasound in detecting joint inflammation in clinically suspect arthralgia patients.
Examined two cohorts of clinically suspect arthralgia patients using bilateral ultrasound.
Described findings of subclinical synovitis and tenosynovitis per hand and joint.
Analyzed the association between ultrasound positivity and the development of inflammatory arthritis.
In cohort 1, 23% had bilateral findings, 20% in the dominant hand, and 10% in the non-dominant hand.
In cohort 2, 10% had bilateral involvement, 12% in the dominant hand, and 8% in the non-dominant hand.
Unilateral scanning of the dominant hand predicted inflammatory arthritis development nearly as effectively as bilateral scanning.

Cite This Study

Boeren et al. (2026) studied this question.

synapsesocial.com/papers/6994058c4e9c9e835dfd6813 https://doi.org/10.3899/jrheum.2025-0373

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Unilateral versus bilateral ultrasound of the hands in patients with clinically suspect arthralgia: what is the difference? A longitudinal study

Discussion

Member takes

Implication

Key Points

Cite This Study

Unilateral versus bilateral ultrasound of the hands in patients with clinically suspect arthralgia: what is the difference? A longitudinal study

Discussion

Member takes

Implication

Key Points

Cite This Study

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