What does this research mean for the field?

The 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline recommends inhaled corticosteroids and a combination of ICS with rapid-onset long-acting β-agonists for asthma management. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

To summarize the clinical practice guidelines for managing asthma in primary care settings for veterans and military personnel.

February 19, 2026Annals of Internal Medicine1 citations

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A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for the Primary Care Management of Asthma

ASAmir SharafkhanehMichael E. DeBakey VA Medical Center EAElizabeth R. AtaydeSouthern Arizona VA Health Care System JCJuhyun ChoNew York City Fire Department

Key Points

To summarize the clinical practice guidelines for managing asthma in primary care settings for veterans and military personnel.
Reviewed current practices for asthma management
Recommended specific inhaled medications
Outlined strategies for managing comorbid conditions
Defined criteria for specialist referral
Strong recommendation for inhaled corticosteroids and combination therapies
Supported management of gastroesophageal reflux disease and obesity
Advised against using indoor air filtration devices
Provided structured decision points for referrals

Abstract

The WG strongly recommended inhaled corticosteroids (ICS) and streamlined management of asthma by suggesting a combination of ICS and rapid-onset long-acting β-agonist as both reliever and controller agents and step-up therapy by increasing ICS and/or adding long-acting anticholinergic agents. The WG also supported the management of symptomatic gastroesophageal reflux disease and obesity for better control of asthma. The WG suggested against the use of indoor air filtration devices. Finally, the WG outlined decision points for referral to a subspecialist.

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Cite This Study

Sharafkhaneh et al. (Mon,) studied this question.

synapsesocial.com/papers/6996a768ecb39a600b3ecf9a https://doi.org/https://doi.org/10.7326/annals-25-03080

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