What question did this study set out to answer?

To outline standardized clinical guidelines for the long-term management and acute exacerbation treatment of adult bronchial asthma in Japan.

February 11, 2017Allergology InternationalOpen Access

Japanese guidelines for adult asthma 2017

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Authors

MIMasakazu IchinoseOsaki Citizen Hospital HSHisatoshi SugiuraTohoku University HNHiroyuki NagaseTeikyo University

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Implication

Clinical guideline outlines stepwise pharmacotherapy and management strategies in adult asthma, highlighting pathways to normalize pulmonary function and curb mortality.

Key Points

To outline standardized clinical guidelines for the long-term management and acute exacerbation treatment of adult bronchial asthma in Japan.
Formulated clinical guidance focusing on chronic airway inflammation, risk factor elimination, and stepped pharmacotherapy.
Established a four-step pharmacotherapeutic protocol incorporating escalating daily doses of inhaled corticosteroids alongside combination controller agents.
Synthesized management recommendations across comorbid conditions including allergic rhinitis, eosinophilic chronic rhinosinusitis, and chronic obstructive pulmonary disease.
Asthma-related mortality decreased to 1.2 per 100,000 patients in 2015 despite rising overall prevalence.
Stepwise maintenance therapy prioritizes inhaled corticosteroids with add-on long-acting beta-2 agonists, leukotriene receptor antagonists, theophylline, and muscarinic antagonists, reserving anti-IgE antibodies and oral steroids for severe phenotypes.
Acute exacerbation management incorporates inhaled beta-2 agonists, aminophylline, systemic corticosteroids, adrenaline, and oxygen based on attack severity.

Cite This Study

Ichinose et al. (2017) studied this question.

synapsesocial.com/papers/6a830a6ec4b5dbf8331f28a0 https://doi.org/10.1016/j.alit.2016.12.005

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Implication

Clinical guideline outlines stepwise pharmacotherapy and management strategies in adult asthma, highlighting pathways to normalize pulmonary function and curb mortality.

Japanese guidelines for adult asthma 2017

Discussion

Member takes

Implication

Key Points

Cite This Study

Japanese guidelines for adult asthma 2017

Discussion

Member takes

Implication

Key Points

Cite This Study

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