Key result
Sarcopenia affects ~36% of outpatient hemodialysis patients.
Why the study?
This study aimed to classify outpatient hemodialysis patients into sarcopenia, dynapenia, presarcopenia, and control groups to clarify their distribution and compare clinical characteristics.
Cross-Sectional (n=177)
Yes
Absolute Event Rate: 35.6% vs 30.5%
In outpatient hemodialysis patients, dynapenia is highly prevalent (28.8%) and distinct from sarcopenia, highlighting the need for early detection using sex-specific functional assessments.
Dynapenia screening may warrant consideration in hemodialysis patients; leaves open prospective validation of functional assessments.
[Purpose] This study aimed to classify patients undergoing outpatient hemodialysis into four groups (sarcopenia, dynapenia, presarcopenia, and controls) to clarify their distribution and compare clinical characteristics. [Participants and Methods] A total of 177 patients undergoing outpatient hemodialysis in the Tokyo urban area were classified into four groups according to skeletal muscle mass index (SMI) and muscle strength. Between-group comparisons were conducted for basic characteristics, body mass index, nutritional indicators, and body fat percentage. [Results] Among the 177 participants, the prevalence of sarcopenia, dynapenia, and presarcopenia was 35.6%, 28.8%, and 5.1%, respectively, and 30.5% were controls. Among participants, those with dynapenia were significantly younger and had higher SMI and than those with sarcopenia. Men participants with dynapenia also had higher extracellular-water to total-body-water ratio and markedly lower grip strength and Five Repetition Sit-to-Stand Test performance compared with controls. Among participants, those with dynapenia had significantly higher SMI and than those with sarcopenia and showed lower grip strength than controls. [Conclusion] Early detection of dynapenia may benefit from test batteries that takes sex differences into consideration.
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Asano et al. (2026) conducted a cross-sectional in Outpatient hemodialysis patients in urban Japan (n=177). Among outpatient hemodialysis patients in urban Japan, the prevalence of sarcopenia was 35.6%, dynapenia 28.8%, presarcopenia 5.1%, and 30.5% were controls.
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