What is already known? Perianal Crohn's disease is a severe phenotype linked to high morbidity and healthcare use. Its impact on quality of life is known, but the roles of disease activity, incontinence, and sexual function remain unclear. What is new here? Active perianal disease significantly worsens quality of life, unlike inactive disease. Older age and lack of maintenance therapy further reduce patient-reported outcomes. How can this study help patient care? Distinguishing active from inactive disease is crucial. Early detection, ongoing therapy, and structured assessment of continence and sexual health can improve quality of life.
Shlomo et al. (Mon,) studied this question.