Key result
Anticoagulation therapy resolves mitral valve leaflet thrombus in an 82-year-old with rheumatic heart disease.
Thrombolytic and anticoagulation therapy can be effective in managing rare native mitral valve thrombosis in patients with rheumatic heart disease presenting with acute stroke.
May support anticoagulation for rare native mitral thrombosis; case report leaves open need for prospective validation.
Rheumatic heart disease remains a significant contributor to cardiovascular morbidity. We report the case of an 82‐year‐old man who presented with acute right‐sided hemiplegia. Transesophageal echocardiography (TEE) showed a thrombus attached to the mitral valve leaflets (MVL). Anticoagulation therapy was initiated, leading to significant thrombus resolution. It spotlights the potential efficacy of thrombolytic and anticoagulation. Committee Approval Number: IR.TBZMED.REC.1403.1018
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Khezerlou et al. (2026) studied this question. Anticoagulation therapy in an 82-year-old with rheumatic heart disease and mitral valve leaflet thrombus led to significant thrombus resolution.
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