Natural gum modified mucin nanocarrier with enhanced mucoadhesion and transcornea infiltration for controlled drug delivery in ocular uveitis therapy

Wahida Binte Naz Aurthy; Nondita Datta; Siew Yee Wong; Xu Li; Asma Rahman; Latiful Bari; Ishtiaque Anwar; M. Tarik Arafat

doi:10.1039/d5ma01442e

January 1, 2026Materials AdvancesOpen Access

Natural gum modified mucin nanocarrier with enhanced mucoadhesion and transcornea infiltration for controlled drug delivery in ocular uveitis therapy

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Key Points

The aim is to develop a mucin nanocarrier that enhances mucoadhesion and drug delivery for treating ocular uveitis.
Developed a natural gum modified mucin nanocarrier.
Tested mucoadhesion and transcornea infiltration capabilities.
Evaluated drug release profiles for controlled delivery.
Increased mucoadhesion compared to traditional treatments.
Enhanced transcornea infiltration improves drug availability.
Demonstrated more effective drug release over time.

Implication

This research demonstrates enhanced drug delivery in ocular uveitis using modified mucin nanocarriers, indicating improved treatment efficiency.

Abstract

Ocular uveitis are a major health concern due to the limited efficacy of current antibiotic eye drops. Conventional treatments require frequent application as they have less bioavailability and show slow...

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Cite This Study

Aurthy et al. (2026) studied this question.

synapsesocial.com/papers/6996a869ecb39a600b3ef1fd https://doi.org/10.1039/d5ma01442e

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Natural gum modified mucin nanocarrier with enhanced mucoadhesion and transcornea infiltration for controlled drug delivery in ocular uveitis therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Natural gum modified mucin nanocarrier with enhanced mucoadhesion and transcornea infiltration for controlled drug delivery in ocular uveitis therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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