What does this research mean for the field?

Financial toxicity affects 66.9% of breast cancer patients, with a moderate burden reflected in a mean COST score of 23.87. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

The aim is to assess the prevalence of financial toxicity among breast cancer patients using the COST tool.

February 19, 2026Clinical Cancer Research

Abstract PS4-11-18: Financial Toxicity in Breast Cancer Patients Assessed by the COST Score: A Systematic Review and Meta-analysis

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Authors

NNN. C. NunesInstituto Nacional do Câncer JSJorge Wagner Esteves da SilvaInstituto Nacional do Câncer KMK. S. de MedeirosLiga Contra el Cancer

Discussion

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Implication

Systematic review demonstrates high financial toxicity in breast cancer patients, highlighting intervention needs.

Key Points

The aim is to assess the prevalence of financial toxicity among breast cancer patients using the COST tool.
Conducted a systematic review and meta-analysis registered in PROSPERO.
Searched databases: PubMed, Cochrane, LILACS, and Embase.
Included studies assessed with the COST tool in breast cancer patients.
Calculated pooled estimates of financial toxicity prevalence and mean COST scores.
Used random-effects models to analyze data and assess heterogeneity.
Identified 13 studies with over 8,400 patients from various countries.
Pooled prevalence of financial toxicity was 66.9% (95% CI: 45.1-88.7%).
The pooled mean COST score was 23.87 (95% CI: 21.25-26.50), indicating moderate financial distress.
Observed a non-significant slight decrease in COST scores over time, suggesting potential worsening of financial toxicity.

Cite This Study

Nunes et al. (2026) studied this question.

synapsesocial.com/papers/6996a879ecb39a600b3ef384 https://doi.org/10.1158/1557-3265.sabcs25-ps4-11-18

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Abstract PS4-11-18: Financial Toxicity in Breast Cancer Patients Assessed by the COST Score: A Systematic Review and Meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Abstract PS4-11-18: Financial Toxicity in Breast Cancer Patients Assessed by the COST Score: A Systematic Review and Meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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