What question did this study set out to answer?

The study aims to explore the factors influencing recruitment and healthcare-seeking behaviors among Black women at risk for de novo metastatic breast cancer.

February 19, 2026Clinical Cancer Research

Abstract PS5-12-04: Initial factors affecting recruitment of Black women in the U.S. Mid-South region diagnosed with or at elevated risk for de novo metastatic breast cancer

Q: What does this research mean for the field?

Race- and gender-concordant recruitment strategies improve engagement of Black women at risk for de novo metastatic breast cancer in the U.S. Mid-South region. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Race- and gender-concordant staffing makes recruiting Black women with metastatic breast cancer feasible despite structural challenges.

Why the study?

Black women face pronounced disparities in de novo metastatic breast cancer incidence and mortality, but the multilevel, culturally specific factors shaping these disparities remain inadequately understood.

Key Points

The study aims to explore the factors influencing recruitment and healthcare-seeking behaviors among Black women at risk for de novo metastatic breast cancer.
Mixed methods design incorporating quantitative data, patient interviews, and observational fieldwork.
Utilization of a socio-ecological model and critical race theory.
Recruitment of 150 participants, half with de novo metastatic breast cancer and half at high risk.
Identification through electronic medical records and racially concordant staff outreach.
219 patients screened, with 30 enrolled (19 dnMBC, 11 high-risk).
Challenges included an ineffective EMR screening tool and social determinants affecting accessibility.
Initial recruitment successes included diverse age and income representation, as well as geographic dispersion.

Structured PICO

Population

Black women in the U.S. Mid-South region (Arkansas, Tennessee, Mississippi) diagnosed with or at elevated risk for de novo metastatic breast cancer (dnMBC). Planned n=150, currently enrolled n=30 (19 dnMBC, 11 high-risk).

Outcome

Barriers that influence screening behaviors and healthcare utilization, unreported structural barriers in social and clinical environments, and clinician perceptions of healthcare quality

Early recruitment findings highlight the need for tailored, community-informed approaches to overcome structural and contextual barriers in disparity-focused cancer research.

Discussion

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Implication

Supports race-concordant recruitment in disparity-focused dnMBC research; leaves open scalability and impact on enrollment equity.

Cite This Study

Curry et al. (2026) studied this question. Recruiting Black women with or at risk for de novo metastatic breast cancer in the U.S. Mid-South is feasible with race- and gender-concordant staff despite structural and social challenges.

synapsesocial.com/papers/6996a8d4ecb39a600b3efee6 https://doi.org/10.1158/1557-3265.sabcs25-ps5-12-04

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Abstract PS5-12-04: Initial factors affecting recruitment of Black women in the U.S. Mid-South region diagnosed with or at elevated risk for de novo metastatic breast cancer

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Abstract PS5-12-04: Initial factors affecting recruitment of Black women in the U.S. Mid-South region diagnosed with or at elevated risk for de novo metastatic breast cancer

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider