Cyanidin-3-O-glucoside chloride inhibits cartilage degeneration and inflammation in TMJOA via YAP/NF-κB signaling pathway

Key Points

• The research aims to explore how cyanidin-3-O-glucoside chloride affects cartilage metabolism and inflammation in TMJOA.
• Investigated the effects of cyanidin-3-O-glucoside chloride on cartilage matrix metabolism
• Analyzed inflammatory responses in TMJOA under compressive stress overload
• Examined the involvement of YAP and NF-κB signaling pathways
• Cyanidin-3-O-glucoside chloride significantly inhibited cartilage degeneration
• Reduced inflammation markers were observed in treated samples
• YAP/NF-κB pathway was shown to be involved in the protective effects of C3G