Key result
Surrogate pregnancy links to more pre-eclampsia, GDM, and conduction abnormalities but similar MACE versus traditional pregnancy.
Why the study?
Does surrogate pregnancy increase the risk of cardiovascular complications compared to traditional pregnancy?
Does surrogate pregnancy increase the risk of cardiovascular complications compared to traditional pregnancy?
While surrogate pregnancy has similar rates of MACE compared to traditional pregnancy, it is associated with higher rates of conduction abnormalities, pre-eclampsia, and GDM, highlighting the need for dedicated cardiovascular care.
May warrant enhanced monitoring for conduction abnormalities, pre-eclampsia, and GDM in surrogates; leaves open causality and generalizability.
Surrogate carriers were more likely to have conduction abnormalities, pre-eclampsia, and GDM, and increased length of hospital stay with similar rates of MACE when compared to non-surrogate carriers. Surrogate pregnancy appears to be a safe and appealing option for women struggling with fertility, however, consideration should be given to the incorporation of dedicated cardiovascular care into the routine follow-up of these patients.
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Mustafa et al. (2026) studied this question. Surrogate pregnancies had more conduction abnormalities, pre-eclampsia, GDM, and longer hospital stays but similar MACE rates compared to traditional pregnancies.
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