Effect of Problem‐Based Learning Combined With Rational Emotive Behavior Therapy on Psychological Outcomes, Self‐Efficacy, Adverse Events, Quality of Life, and Treatment Compliance in Breast Cancer Care: A Non‐Randomized Study

To evaluate the effectiveness of combined problem‐based learning (PBL) and rational emotive behavior therapy (REBT) on Psychological Outcomes, Self‐Efficacy, Adverse Events, Quality of Life, and Treatment Compliance in breast cancer care. In this non‐randomized study conducted at a tertiary hospital in China, 180 patients with breast cancer treated between October 2021 and August 2022 were divided into a control group ( n = 90) receiving conventional education and a study group ( n = 90) receiving PBL combined with REBT. Outcomes were assessed using validated scales including the Hamilton Anxiety/Depression Rating Scales, EORTC QLQ‐C30, General Self‐Efficacy Scale, a hospital‐designed compliance questionnaire, and adverse event follow‐up. After intervention, the study group demonstrated significantly greater improvements in psychological outcomes ( p < 0.05), self‐efficacy ( p < 0.05), lower adverse event rates (13.33% vs. 31.11%; p < 0.01), quality of life domains ( p < 0.05), treatment compliance ( p < 0.05), compared to the control group. The combined PBL and REBT approach enhances postoperative care for patients with breast cancer by improving psychological outcomes (e.g., reducing anxiety), enhancing self‐efficacy, minimizing adverse events, improving quality of life, and promoting treatment compliance.