Key result
Electrical cardioversion for AF can trigger marked QTc prolongation and TdP even without prior repolarization issues.
Why the study?
Electrical cardioversion is generally safe for restoring sinus rhythm in atrial fibrillation, but it may rarely precipitate significant proarrhythmic complications.
Electrical cardioversion for atrial fibrillation can rarely precipitate life-threatening proarrhythmic complications like marked QT prolongation and torsades de pointes, necessitating vigilant post-procedural monitoring.
May warrant post-cardioversion QTc monitoring in AF; leaves open incidence and predictors.
Electrical cardioversion is a widely used and generally safe procedure for restoring sinus rhythm in atrial fibrillation. However, it may rarely precipitate significant proarrhythmic complications. We report the case of a 35-year-old woman with a history of atrial septal defect closure who presented with persistent symptomatic atrial fibrillation. She underwent successful synchronized direct current cardioversion, but immediately developed marked prolongation of the corrected QT interval (>600 ms) followed by recurrent episodes of torsades de pointes, one requiring defibrillation. Intravenous magnesium was administered, but QT prolongation persisted in association with hypotension and bradycardia. Dopamine infusion was initiated to increase heart rate, which contributed to gradual QT normalization. The patient recovered fully without recurrence of arrhythmia. This case highlights a rare but potentially life-threatening complication of cardioversion and underscores the importance of vigilant post-procedural monitoring and timely intervention, even in patients without prior repolarization abnormalities.
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Elzain et al. (2025) studied this question. Electrical cardioversion of atrial fibrillation can cause marked QTc prolongation (>600 ms) and torsades de pointes even in young patients without prior repolarization issues.
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