Key result
IV amiodarone followed by hemodialysis-induced hypokalemia triggers excessive QT prolongation and TdP in a case.
Population
A 77-year-old on renal dialysis for end-stage renal disease with heart failure and AF
Design
Case report
Authors
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Alerts clinicians to monitor QT with IV amiodarone plus hypokalemia; hypothesis-generating for TdP risk in cardiomyopathy.
Case Report (n=1)
Intravenous amiodarone can induce torsades de pointes in patients with tachycardia-induced cardiomyopathy, especially when complicated by hemodialysis-induced hypokalemia.
Yonai et al. (2020) conducted a case report in Tachycardia-induced-cardiomyopathy, atrial fibrillation, end-stage renal disease (n=1). Intravenous amiodarone was evaluated on Torsades de pointes (TdP). Intravenous amiodarone therapy followed by hemodialysis-induced hypokalemia led to excessive QT and Tp-e interval prolongation and numerous episodes of torsades de pointes in a 77-year-old patient.
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