Key result
IV amiodarone linked to reversible TdP in a patient with heart failure.
Population
1 patient, 61-year-old woman with severe mitral valve regurgitation, atrial fibrillation, and heart failure…
Design
Case_report
Follow-up
5 days after discontinuation
Authors
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May prompt ECG monitoring for TdP in HF patients on IV amiodarone plus digitalis; case report leaves risk quantification open.
Case Report (n=1)
Amiodarone can induce Torsade de pointes, particularly in patients with heart failure taking digitalis, despite its generally low proarrhythmic risk.
Jhuo et al. (2013) conducted a case report in Heart failure, atrial fibrillation, and severe mitral valve regurgitation (n=1). Amiodarone was evaluated on Torsade de pointes (TdP). Intravenous amiodarone therapy induced Torsade de pointes in a 61-year-old woman with heart failure, which resolved after drug discontinuation.
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