Key result
Intravenous amiodarone was associated with a 1.5% incidence of drug-induced Torsades de Pointes (4 of 268 patients), with no immediate or late mortality observed.
Why the study?
What is the incidence of drug-induced Torsades de Pointes in patients receiving intravenous amiodarone?
Population
268 patients receiving intravenous amiodarone
Design
Cohort
Follow-up
5-10 months
Authors
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TdP with IV amiodarone warrants monitoring; leaves open risk predictors and incidence via prospective studies.
Observational (n=268)
What is the incidence of drug-induced Torsades de Pointes in patients receiving intravenous amiodarone?
Intravenous amiodarone is associated with a ~1.5% incidence of drug-induced Torsades de Pointes, which has a favorable prognosis if recognized and treated promptly.
Shenthar et al. (2017) conducted an observational in Ventricular tachycardia, atrial flutter/fibrillation, or incessant atrial tachycardia (n=268). Intravenous amiodarone was evaluated on Incidence of drug-induced Torsades de Pointes (TdP). Intravenous amiodarone was associated with a 1.5% incidence of drug-induced Torsades de Pointes (4 of 268 patients), with no immediate or late mortality observed.
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