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This research demonstrates the role of bifunctional dehydratases in ansamitocin biosynthesis, highlighting its importance in antitumor compound formation.
Ansamitocin, a potent antitumor polyketide compound from Actinosynnema pretiosum , is assembled by a modular type I polyketide synthase (PKS-I).
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Guo et al. (2026) studied this question.
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