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February 21, 2026Biophysical Journal

BPS2026 – Single-channel currents to cable theory: A boundary layer framework for ionic transport near membranes

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Authors

HRHyeongjoo RowQB3JFJoshua B. FernandesJFJafar FarhadiUniversity of California, Berkeley

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Implication

Boundary layer theory demonstrates effects of ion channels on charge transport and electric fields in membranes.

Key Points

  • This research aims to bridge the gap between microscopic ionic currents and macroscopic bioelectric responses.
  • Developed a boundary layer theory for ionic transport near membranes.
  • Analyzed membrane geometries including cylindrical and planar membranes.
  • Validated results using large-scale simulations.
  • Found that ion channels influence charge transport dynamics through electric fields.
  • Demonstrated that effective diffusivity scales linearly with system size.
  • Identified distinct regimes of membrane potential and charging behaviors.

Cite This Study

Row et al. (2026) studied this question.

synapsesocial.com/papers/69990e015b97ab4c14ac2f35https://doi.org/10.1016/j.bpj.2025.11.2395
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1BPS2026 – Electrical signal propagation on membranes: From single to multiple channels2026
  2. 2Studies on Poisson–Nernst–Planck Systems with Large Permanent Charges Under Relaxed Neutral Boundary Conditions2025 · 2 citations
  3. 3BPS2026 – Electromechanics of charged-biological membranes: Dynamics, instabilities, and signaling2026
  4. 4BPS2026 – Capacitive response of biological membranes2026
  5. 5THE INFLUENCE OF SMALL PERMANENT CHARGES AND PARTIAL BOUNDARY CONDITIONS ON INDIVIDUAL FLUXES VIA POISSON-NERNST-PLANCK SYSTEMS2026