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This correspondence discusses confidence regions and highlights heterogeneity in diagnostic test accuracy meta-analyses.
• This correspondence discusses key methodological considerations specific to diagnostic test accuracy meta-analyses. • It explains why intervention-style heterogeneity metrics and separate pooling mislead in DTA reviews. • It highlights the need for HSROC plots with confidence and prediction regions. • It calls for transparent handling of sparse data and appropriate assessment of heterogeneity and bias. This correspondence discusses key methodological considerations specific to diagnostic test accuracy meta-analyses. It explains why intervention-style heterogeneity metrics and separate pooling mislead in DTA reviews. It highlights the need for HSROC plots with confidence and prediction regions. It calls for transparent handling of sparse data and appropriate assessment of heterogeneity and bias.
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Javier Arredondo Montero (2026) studied this question.
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