A theranostic study demonstrates correlation of PET response to therapeutic outcomes in tumor models using scandium agents.
Two chemically identical, PSMA-targeting radioscandium pharmaceuticals demonstrated in vivo stability, specificity and retention in PSMA+ tumor models. A theranostic study showed that a higher ⁴³Sc PET SUVmean was strongly correlated to therapeutic response from the ⁴⁷Sc agent, demonstrating that ⁴³Sc and ⁴⁷Sc can be used as an elementally matched theranostic pair.
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Cingoranelli et al. (2026) studied this question.
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