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February 21, 2026International Review of Psychiatry

Targeting active forgetting with non-invasive stimulation: toward novel treatments for intrusive memories in PTSD

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Authors

EAElva ArulchelvanVSVanneste Sven

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Overview

This review explores non-invasive stimulation techniques to enhance memory forgetting in individuals with PTSD, suggesting new treatment avenues.

Key Points

  • The review aims to understand active forgetting mechanisms in PTSD and evaluate non-invasive stimulation methods.
  • Mapped neural correlates of active forgetting in PTSD through literature review.
  • Explored neurotransmitters involved in active forgetting processes.
  • Reviewed various non-invasive neurostimulation techniques like TMS and tDCS aimed at enhancing memory forgetting.
  • Identified future research questions regarding active forgetting interventions.
  • Active forgetting is regulated by specific brain circuits in the hippocampus and prefrontal cortex.
  • Non-invasive stimulation methods show potential in altering memory processes related to PTSD.
  • Neurotransmitters play a crucial role in facilitating active forgetting, though the specific pathways are still being explored.

Cite This Study

Arulchelvan et al. (2026) studied this question.

synapsesocial.com/papers/69994ba9873532290d01fd63https://doi.org/10.1080/09540261.2026.2631028
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