Shows limited impact of fungal PCR positivity on management in immunocompromised young individuals, suggesting a need for further evaluation.
We describe use of Aspergillus and Mucorales PCRs in 54 immunocompromised children and young adults undergoing 66 bronchoscopies. Test positivity was 2/54 (3.2%) and 1/59 (1.7%) for Aspergillus and Mucorales. For Aspergillus PCRs, 4/54 (7.4%) positively impacted management, compared to 4/59 (6.8%) for Mucorales. Fungal PCRs may influence care of immunocompromised patients, though overall impact was limited.
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Brammer et al. (2026) studied this question.
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