What question did this study set out to answer?

This research aims to understand how maternal nutrition influences epigenetic outcomes during pregnancy and early lactation.

February 21, 2026NMO journalOpen Access

Precision Nutriepigenomics and Developmental Origins of Health and Disease: A Systematic Review from Pregnancy to Early Lactation

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This research aims to understand how maternal nutrition influences epigenetic outcomes during pregnancy and early lactation.
Conducted a systematic review following PRISMA 2020 guidance.
Screened 3600 titles and abstracts, assessed 250 full texts, and included 45 studies based on specific criteria.
Evaluated risk of bias using various established scales and synthesized findings with a structured narrative approach.
Identified key nutrients influencing DNA methylation and other epigenetic marks.
Balanced one-carbon nutrition and adequate Vitamin D showed positive impacts, while iodine excess led to adverse effects.
Recommendations for future trials emphasize the importance of incorporating epigenetic endpoints.

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Implication

Systematic review examines nutritional influences on epigenetic outcomes from pregnancy to early lactation, suggesting modifiable pathways for health.

Cite This Study

Bachnas et al. (2026) studied this question.

synapsesocial.com/papers/69994c80873532290d021097 https://doi.org/10.4103/jnmo.jnmo_114_25

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Implication

Systematic review examines nutritional influences on epigenetic outcomes from pregnancy to early lactation, suggesting modifiable pathways for health.

Precision Nutriepigenomics and Developmental Origins of Health and Disease: A Systematic Review from Pregnancy to Early Lactation

Key Points

Discussion

Implication

Cite This Study

Precision Nutriepigenomics and Developmental Origins of Health and Disease: A Systematic Review from Pregnancy to Early Lactation

Key Points

Discussion

Implication

Cite This Study

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