Abstract B043: IInhibition of PSGL-1 overcomes immune suppression and immunotherapy resistance in PDAC

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Abstract 1359: Rewiring CD8+T cell responses to PD-1 immune checkpoint blockade in PDAC by preventing terminal exhaustion via the inhibitory receptor PSGL-12024
2. 2Abstract B058: Rewiring CD8+ T cell responses to PD-1 immune checkpoint blockade in PDAC via the inhibitory receptor PSGL-12024
3. 3Disabling PSGL-1 abrogates immune suppression and resistance to PD-1 blockade in pancreatic cancer2025
4. 4Abstract B033: Leveraging PSGL-1 blockade to elicit responses to anti-PD-1 immunotherapy resistant melanoma2026
5. 5Abstract 1561: Overcoming immunosuppression in pancreatic cancer: Efficacy of polyamine blockade and anti-PD-1 combinational therapy2026