What question did this study set out to answer?

To describe the design, recruitment, and baseline profile of a prospective pediatric cohort examining the impact of environmental and genetic exposures from fetal life up to 18 years of age.

March 10, 2015Paediatric and Perinatal Epidemiology

The Odense Child Cohort: Aims, Design, and Cohort Profile

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Authors

HKHenriette Boye KyhlOdense University Hospital TJTina Kold JensenUniversity of Southern Denmark TBTorben BaringtonOdense University Hospital

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Implication

Cohort study reveals baseline characteristics and biobank data in 2,549 children, establishing an infrastructure to assess environmental determinants of lifelong health.

Key Points

To describe the design, recruitment, and baseline profile of a prospective pediatric cohort examining the impact of environmental and genetic exposures from fetal life up to 18 years of age.
Recruited 2,874 of 6,707 eligible pregnant women (43% participation rate) between January 2010 and December 2012, retaining 2,500 active families with 2,549 children.
Collected maternal blood samples at 10 and 28 weeks of gestation, paternal blood samples, infant blood samples, questionnaire data, anthropometric measurements, and health registry records from participants and non-participants.
Blood samples were donated by 60% of mothers at 10 weeks of gestation, 58% of mothers at 28 weeks of gestation, 64% of fathers, and 46% of children.
Routine clinical examinations were attended by 78% of children, and questionnaires achieved an average completion rate of 69%.
Participating mothers differed significantly from non-participants across age, body mass index, smoking habits, parity, education level, and ethnicity, whereas infants had similar sex distribution and delivery modes.

Cite This Study

Kyhl et al. (2015) studied this question.

synapsesocial.com/papers/699a33262dac970dae1eb099 https://doi.org/10.1111/ppe.12183

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Implication

Cohort study reveals baseline characteristics and biobank data in 2,549 children, establishing an infrastructure to assess environmental determinants of lifelong health.

The Odense Child Cohort: Aims, Design, and Cohort Profile

Discussion

Member takes

Implication

Key Points

Cite This Study

The Odense Child Cohort: Aims, Design, and Cohort Profile

Discussion

Member takes

Implication

Key Points

Cite This Study

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