A gastrointestinal soft tissue tumour with PTCH1::GLI1 fusion | Synapse
February 22, 2026
A gastrointestinal soft tissue tumour with PTCH1::GLI1 fusion
Key Points
To describe a rare gastrointestinal soft tissue neoplasm associated with PTCH1::GLI1 fusion.
Case report of an identified gastrointestinal soft tissue tumour.
Clinical evaluation of the neoplasm and associated characteristics.
Identified a rare case of a soft tissue neoplasm with PTCH1::GLI1 fusion.
The tumour type poses challenges in understanding treatment options.
Abstract
GLI1-activated tumours constitute a distinct subclass of soft tissue neoplasm. Due to their rarity, the clinical course and treatment options for these neoplasms are not well understood.